Symptoms & Signs
- Bleeding into the skin or mucus membranes
- Changes in consciousness
- Confusion
- Easy fatigue
- Fever
- Headache
- Heart rate over 100 beats per minute
- Pallor
- Purplish spots in the skin produced by small bleeding vessels near the surface of the skin (purpura)
- Shortness of breath on exertion
- Speech changes
- Weakness
- Yellowish color to the skin (jaundice)
Diagnosis & Tests
- Bilirubin
- Blood smear
- CBC
- Creatinine level
- Lactate dehydrogenase (LDH) level
- Mucus membrane biopsy
- Platelet count
- Urinalysis
Pictures & Images
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Thrombotic thrombocytopenic purpura: Overview, Causes
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Thrombotic thrombocytopenic purpura: Symptoms & Signs, Diagnosis & Tests
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Thrombotic thrombocytopenic purpura: Treatment
Review Date : 3/2/2009
Reviewed By : David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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