What is Rybix ODT?

Tramadol is a narcotic-like pain reliever.
Tramadol is used to treat moderate to severe pain. Tramadol extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock.
Tramadol may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rybix ODT?

You should not take tramadol if you have ever been addicted to drugs or alcohol.
Seizures (convulsions) have occurred in some people taking tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.
Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal. Overdose symptoms may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, feeling light-headed, fainting, or coma.
Tramadol may be habit-forming. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Never share tramadol with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Tramadol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.
Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.

What should I discuss with my healthcare provider before taking Rybix ODT?

You should not take tramadol if you are allergic to it, if you have ever been addicted to drugs or alcohol, if you have ever attempted suicide, if you are currently intoxicated (drunk), or if you have recently used any of the following drugs:

alcohol
narcotic pain medicine
sedatives or tranquilizers (such as Valium)
medicine for depression or anxiety
medicine for mental illness (such as bipolar disorder, schizophrenia); or
street drugs

Seizures have occurred in some people taking tramadol. Your risk of a seizure may be higher if you have any of these conditions:

a history of drug or alcohol addiction
a history of epilepsy or other seizure disorder
a history of head injury
a metabolic disorder; or
if you are also taking an antidepressant, muscle relaxer, or medicine for nausea and vomiting

Talk with your doctor about your individual risk of having a seizure while taking tramadol.
If you have any of these other conditions, you may need a tramadol dose adjustment or special tests:

kidney disease (or if you are on dialysis)
cirrhosis or other liver disease
a stomach disorder; or
a history of depression, mental illness, or thoughts of suicide

FDA pregnancy category C. It is not known whether tramadol will harm an unborn baby. Tramadol may cause serious or fatal side effects in a newborn if the mother uses the medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Tramadol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not give this medication to anyone younger than 18 years old without the advice of a doctor.

Rybix ODT Side Effects

What are the possible side effects of Rybix ODT?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using tramadol and call your doctor at once if you have any of these serious side effects:

agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting
seizure (convulsions)
a red, blistering, peeling skin rash; or
shallow breathing, weak pulse

Less serious side effects may include:

dizziness, drowsiness, weakness
nausea, vomiting, constipation, loss of appetite
blurred vision
flushing (redness, warmth, or tingly feeling); or
sleep problems (insomnia)

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Rybix ODT Interactions

What other drugs affect Rybix ODT?

You may be more likely to have a seizure (convulsions) if you take tramadol while you are using certain other medicines. Do not take tramadol without telling your doctor if you also use any of the following medications:

an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or
an antidepressant such as amitriptyline (Elavil), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor); paroxetine (Paxil), or sertraline (Zoloft)

Cold or allergy medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by tramadol. Tell your doctor if you regularly use any of these medicines, or any other pain medication.
Tell your doctor about all other medicines you use, especially:

carbamazepine (Tegretol)
warfarin (Coumadin)
digoxin (Lanoxin, Lanoxicaps)
ketoconazole (Extina, Ketozole, Nizoral, Xolegal)
erythromycin (E-Mycin, E.E.S., Ery-Tab)
migraine headache medicine such as sumatriptan (Imitrex, Treximet)
rifampin (Rifadin, Rimactane, Rifater)
St. John’s wort
quinidine (Quin-G); or
drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety)

This list is not complete and other drugs may interact with tramadol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What should I avoid while taking Rybix ODT?

Do not drink alcohol while you are taking tramadol. Alcohol may cause a dangerous decrease in your breathing when used together with tramadol.
Tramadol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Rybix ODT Dosage

How should I take Rybix ODT?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Tramadol can be taken with or without food, but take it the same way each time.
Do not crush, chew, or break a tramadol tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.
This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.
To take tramadol orally disintegrating tablets (Rybix):

Keep the tablet in its blister pack until you are ready to take it
Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away
Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing
Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet

If you use the tramadol extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.
Tramadol may be habit-forming. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Do not change your dose without talking to your doctor.
Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Tramadol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I overdose on Rybix ODT?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A tramadol overdose can be fatal.
Overdose symptoms may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, feeling light-headed, fainting, or coma.

What happens if I miss a dose of Rybix ODT?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Sourced from everydayhealth.com

Rybix ODT