What is Micafungin?
Micafungin is an antifungal antibiotic.
Micafungin is used to treat infections caused by the Candida fungus. Micafungin is also used to prevent Candida fungal infections in stem cell transplant patients.
Micafungin may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Micafungin?
You should not use this medication if you are allergic to micafungin.
Before using micafungin, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Before receiving micafungin, tell your doctor if you are also using sirolimus (Rapamune), itraconazole (Sporanox), or nifedipine (Adalat, Procardia).
Micafungin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.
You may need to receive this medication for several weeks.
You should not use this medication if you are allergic to micafungin.
Before using micafungin, tell your doctor if you are allergic to any drugs, or if you have:
- liver disease; or
- kidney disease
If you have any of these conditions, you may need a dose adjustment or special tests to safely receive this medication.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether micafungin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Micafungin Side Effects
What are the possible side effects of Micafungin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- pale or yellowed skin, dark colored urine, confusion or weakness
- stomach pain, itching, clay-colored stools, jaundice (yellowing of the skin or eyes)
- fever, chills, body aches, flu symptoms
- easy bruising or bleeding
- urinating less than usual or not at all
- drowsiness, mood changes, increased thirst, loss of appetite, nausea and vomiting
- uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; or
- swelling of your hands or feet
Less serious side effects may include:
- warmth, redness, or tingly feeling under your skin
- mild nausea, vomiting, or stomach pain
- diarrhea, constipation, indigestion
- headache
- sleep problems (insomnia)
- mild itching or skin rash; or
- pain, swelling, or tenderness where the medicine was injected
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Micafungin Interactions
What other drugs affect Micafungin?
The following drugs can interact with micafungin. Tell your doctor if you are using any of these:
- sirolimus (Rapamune)
- itraconazole (Sporanox); or
- nifedipine (Adalat, Procardia)
This list is not complete and there may be other drugs that can interact with micafungin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
What should I avoid while taking Micafungin?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using micafungin.
Micafungin Dosage
How should I take Micafungin?
Micafungin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.
You will need to mix micafungin with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.
Micafungin must be given slowly through an IV infusion, and each injection can take at least 1 hour to complete. Do not mix micafungin with any other medicines, or give other medicines through the same IV line.
Micafungin is usually given once daily. You may need to receive this medication for several weeks.
Do not shake the medicine bottle (vial). Vigorous shaking can ruin the medicine. Do not mix your micafungin dose into an IV bag until you are ready to give yourself an injection. Do not use the medication if it has changed colors or has any particles in it. Call your doctor for a new prescription.
After mixing this medicine, do not expose it to light. Cover the IV bag during your infusion to protect the medicine from light. Use the medicine within 24 hours after mixing.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
If you store micafungin at home, keep it at room temperature away from moisture, heat, and light. Mixed medicine can be stored at room temperature but must be used within 24 hours after mixing.
What happens if I overdose on Micafungin?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a micafungin overdose are not known.
What happens if I miss a dose of Micafungin?
Call your doctor for instructions if you miss a dose.
Edited from everydayhealth.com