Coccidioidomycosis : Symptoms & Signs, Diagnosis & Tests

Symptoms & Signs

Symptoms of coccidioidomycosis can include:

  • Blood-tinged sputum
  • Change in mental status
  • Chest pain (can vary from a mild sense of constriction to severe pain, may get worse when taking a deep breath)
  • Chills
  • Cough
  • Fever
  • Headache
  • Joint stiffness
  • Loss of appetite
  • Muscle aches
  • Muscle stiffness
  • Neck stiffness or shoulder stiffness
  • Night sweats
  • Rash, may be painful, red nodules on lower legs (erythema nodosum)
  • Sensitivity to light
  • Sweating, excessive
  • Weight loss
  • Wheezing

Additional symptoms associated with this disease:

  • Ankle, feet, and leg swelling
  • Arthritis
  • Enlarged or draning lymph nodes
  • Joint pain
  • Joint swelling

See also skin lesion of coccidioidomycosis.

Diagnosis & Tests

  • CBC with differential
  • Chest x-ray
  • Coccidioidin or Spherulin skin test
  • Serum coccidioides complement fixation titer
  • Sputum culture
  • Sputum smear (KOH test)

Review Date : 12/3/2008
Reviewed By : David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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