New treatment for overactive bladder patients: approved FDA

(Reuters) – With those who are suffering with bladder problems now can be treated be popular kind of wrinkle method by using Allergan’s Botox which has already approved by U.S. drug regulators.

Botox can be injected into the bladder of patient who lose bladder control because of damage to the nervous system, through conditions such as multiple sclerosis or spinal cord injury.

The drug received a similar approval in Europe earlier this month.

At the same time, the company will also try to make Botox accepted on the market to a broader population of patients with overactive bladder, the company’s CEO David Pyott told Reuters earlier this month.

“This approval is positive as it may bode well for the eventual approval of Botox in idiopathic (of unknown cause) overactive bladder,” Leerink Swann analyst Seamus Fernandez said in a research note.

Predicted sales is expected to about $40 million for the current bladder label by 2017, and $210 million in 2017 for the broader label, which he expects Allergan to file for next year.

Overactive bladder, caused by uncontrollable contractions of the bladder, causes frequent urination, urgent need to urinate and inability to control urination.

A single injection of Botox into the bladder can relax it and increase its storage capacity, with the effect lasting for about nine months.

About 60 to 80 percent of patients with multiple sclerosis or spinal cord injury experience some form of bladder problems, Allergan said, out of 350,000 such patients in the United States.

“It’s very smart for management to build out these therapeutic indications for Botox because it’s more difficult for competitors to get into these areas as opposed to the cosmetic side, where they’re probably going to see continued market share losses,” said Michael Waterhouse, analyst at Morningstar.

Botox’ active ingredient is a toxin that blocks nerve signals. It gets about half its annual sales of $1.5 billion from reducing wrinkles. It is also approved to prevent migraine headaches and to treat upper limb spasticity, neck pain from cervical dystonia and certain types of eye muscle problems and spasms of the eyelids.

Botox offers a new treatment option for patients who do not respond to standard treatments for bladder control, pills called anticholinergics, which include oxybutynin and Astellas and GlaxoSmithKline’s Vesicare.

Allergan shares closed up 3 percent at $77.90 at the end of regular trading Wednesday on the New York Stock Exchange, outperforming a 0.5 percent increase in the Arca Pharmaceutical Index of large U.S. and European drugmakers.

US Approves Botox for Bladder Control

The face-freezing pharmaceutical injection Botox gained another medical use on Wednesday when the US government approved it for use in some patients with overactive bladders.

The new application was given the nod by the US Food and Drug Administration to treat people with multiple sclerosis or spinal cord injury who suffer from urinary incontinence and must manage it with medication or a catheter.

“Urinary incontinence associated with neurologic conditions can be difficult to manage,” said George Benson, deputy director of FDA’s division of Reproductive and Urologic Products.

“Botox offers another treatment option for these patients.”

The new method allows a physician to inject Botox into a patient’s bladder, where it relaxes the muscles and allows more urine to be stored.

Clinical studies showed such injections could decrease episodes of urinary incontinence for a period of nine months.

Botox, which is marketed by the California-based Allergan, is also approved for treatment of chronic migraines, severe underarm sweating, eyelid twitching and certain kinds of muscle stiffness, the FDA said.

The drug is made from a toxin produced by the bacterium Clostridium botulinum. In other forms it can cause a deadly type of food poisoning called botulism, according to the National Institutes of Health.

Source: yahoo

Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)

What is Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, diphenhydramine, and pseudoephedrine is used to treat runny or stuffy nose, sinus congestion, sneezing, and pain or fever caused by allergies or the common cold.

Acetaminophen, diphenhydramine, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver.

Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, or pseudoephedrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

What should I discuss with my healthcare provider before taking Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Do not take this medication if you are allergic to acetaminophen, diphenhydramine, or pseudoephedrine, or to other antihistamines or decongestants, diet pills, stimulants, or ADHD medications.

Ask a doctor or pharmacist about using acetaminophen, diphenhydramine, and pseudoephedrine if you have:

  • heart disease or high blood pressure
  • liver disease, alcoholism, or cirrhosis of the liver
  • glaucoma
  • kidney disease
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Sinus(obsolete) Side Effects

What are the possible side effects of Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • urinating less than usual or not at all
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

  • blurred vision
  • dry mouth
  • mild loss of appetite
  • nausea, stomach pain, constipation
  • dizziness, drowsiness
  • problems with memory or concentration
  • ringing in your ears
  • restless or excitability (especially in children)
  • sleep problems (insomnia)
  • skin rash, redness, or itching; or
  • warmth, tingling, or redness under your skin

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Sinus(obsolete) Interactions

What other drugs affect Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Also tell your doctor if you are using any of the following drugs:

  • an antidepressant
  • a bronchodilator
  • a diuretic (water pill)
  • gout medications
  • blood pressure medication
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • seizure medication
  • isoniazid
  • zidovudine (Retrovir, AZT)
  • aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others); or
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

This list is not complete and there may be other drugs that can interact with acetaminophen, diphenhydramine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, and pseudoephedrine are contained in many combination medicines. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP, diphenhydramine, or pseudoephedrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Benadryl Allergy Sinus(obsolete) Dosage

How should I take Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

An overdose of acetaminophen can cause serious harm. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One acetaminophen, diphenhydramine, and pseudoephedrine pill may contain up to 500 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Take this medication with food or milk if it upsets your stomach.

Drink extra fluids while you are taking acetaminophen, diphenhydramine, and pseudoephedrine.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I overdose on Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include feeling restless or nervous, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy Sinus(obsolete) (Apap/Diphenhydramine/Pseudoephedrine)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)

What is Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen and pseudoephedrine is used to treat stuffy nose, sinus congestion, and pain or fever caused by the common cold.

Acetaminophen and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver.

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you take to see if it contains acetaminophen (sometimes abbreviated as “APAP”) or pseudoephedrine.

If you drink more than three alcoholic beverages per day, do not take this medication without your doctor’s advice.

What should I discuss with my healthcare provider before taking Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Do not use this medication if you are allergic to acetaminophen or pseudoephedrine.

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Before taking acetaminophen and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

  • cirrhosis or other liver disease
  • a history of alcoholism
  • heart disease or high blood pressure
  • glaucoma
  • an enlarged prostate
  • diabetes; or
  • a thyroid disorder

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before taking acetaminophen and pseudoephedrine, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Acetaminophen and pseudoephedrine may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Sinus Headache Side Effects

What are the possible side effects of Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • severe dizziness, anxiety, restless feeling, or nervousness
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

  • mild loss of appetite
  • warmth, tingling, or redness under your skin
  • feeling excited or restless
  • sleep problems (insomnia); or
  • skin rash or itching

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Sinus Headache Interactions

What other drugs affect Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • isoniazid
  • zidovudine (Retrovir, AZT)
  • medicines to treat high blood pressure
  • gout medications such as probenecid (Benemid) or sulfinpyrazone
  • seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton)
  • stimulants (caffeine, diet pills, ADHD medications such as Ritalin or Adderall)
  • an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others; or
  • a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

This list is not complete and there may be other drugs that can interact with acetaminophen and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”) and pseudoephedrine are contained in many combination medicines. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP, or pseudoephedrine.

If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) of acetaminophen per day.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Benadryl Allergy Sinus Headache Dosage

How should I take Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

Drink extra fluids while you are taking acetaminophen and pseudoephedrine.

An overdose of acetaminophen can cause serious harm. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One acetaminophen and pseudoephedrine tablet may contain up to 500 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure the liquid form of acetaminophen and pseudoephedrine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I overdose on Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, dizziness, drowsiness, nausea, vomiting, diarrhea, stomach pain, loss of appetite, increased sweating, seizure (convulsions), or coma.

What happens if I miss a dose of Benadryl Allergy Sinus Headache (Acetaminophen Pseudoephedrine)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)

What is Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of diphenhydramine and pseudoephedrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Diphenhydramine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Diphenhydramine and pseudoephedrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take diphenhydramine and pseudoephedrine if you have:

  • kidney disease
  • diabetes
  • glaucoma
  • heart disease or high blood pressure
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Diphenhydramine and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Sinus Fastmelt Side Effects

What are the possible side effects of Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • confusion, hallucinations, unusual thoughts or behavior
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • urinating less than usual or not at all

Less serious side effects may include:

  • blurred vision
  • dry mouth
  • nausea, stomach pain, constipation
  • mild loss of appetite, stomach upset
  • warmth, tingling, or redness under your skin
  • sleep problems (insomnia)
  • restless or excitability (especially in children)
  • skin rash or itching
  • dizziness, drowsiness
  • problems with memory or concentration; or
  • ringing in your ears

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Sinus Fastmelt Interactions

What other drugs affect Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by diphenhydramine. Tell your doctor if you regularly use any of these medicines, or any other cold or allergy medicines.

Tell your doctor about all other medications you use, especially:

  • medicines to treat high blood pressure
  • a diuretic (water pill)
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others)
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or
  • antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others

This list is not complete and there may be other drugs that can interact with diphenhydramine and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Benadryl Allergy Sinus Fastmelt Dosage

How should I take Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Take this medicine with a full glass of water.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The orally disintegrating tablets (such as Benadryl Childrens Allergy & Cold) should be placed in the mouth and allowed to dissolve. Do not swallow the disintegrating tablet whole. Allow it to dissolve in your mouth without chewing.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I overdose on Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy Sinus Fastmelt (Diphenhydr Amine Pseudoephedrine)?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)

What is Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of diphenhydramine and pseudoephedrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Diphenhydramine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Diphenhydramine and pseudoephedrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take diphenhydramine and pseudoephedrine if you have:

  • kidney disease
  • diabetes
  • glaucoma
  • heart disease or high blood pressure
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Diphenhydramine and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Sinus Side Effects

What are the possible side effects of Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • confusion, hallucinations, unusual thoughts or behavior
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • urinating less than usual or not at all

Less serious side effects may include:

  • blurred vision
  • dry mouth
  • nausea, stomach pain, constipation
  • mild loss of appetite, stomach upset
  • warmth, tingling, or redness under your skin
  • sleep problems (insomnia)
  • restless or excitability (especially in children)
  • skin rash or itching
  • dizziness, drowsiness
  • problems with memory or concentration; or
  • ringing in your ears

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Sinus Interactions

What other drugs affect Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by diphenhydramine. Tell your doctor if you regularly use any of these medicines, or any other cold or allergy medicines.

Tell your doctor about all other medications you use, especially:

  • medicines to treat high blood pressure
  • a diuretic (water pill)
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others)
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or
  • antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others

This list is not complete and there may be other drugs that can interact with diphenhydramine and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Benadryl Allergy Sinus Dosage

How should I take Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Take this medicine with a full glass of water.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The orally disintegrating tablets (such as Benadryl Childrens Allergy & Cold) should be placed in the mouth and allowed to dissolve. Do not swallow the disintegrating tablet whole. Allow it to dissolve in your mouth without chewing.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I overdose on Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy Sinus (Diphenhydr Amine Pseudoephedrine)?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)

What is Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of diphenhydramine and pseudoephedrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Diphenhydramine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Diphenhydramine and pseudoephedrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take diphenhydramine and pseudoephedrine if you have:

  • kidney disease
  • diabetes
  • glaucoma
  • heart disease or high blood pressure
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Diphenhydramine and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Decongestant Side Effects

What are the possible side effects of Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • confusion, hallucinations, unusual thoughts or behavior
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • urinating less than usual or not at all

Less serious side effects may include:

  • blurred vision
  • dry mouth
  • nausea, stomach pain, constipation
  • mild loss of appetite, stomach upset
  • warmth, tingling, or redness under your skin
  • sleep problems (insomnia)
  • restless or excitability (especially in children)
  • skin rash or itching
  • dizziness, drowsiness
  • problems with memory or concentration; or
  • ringing in your ears

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Decongestant Interactions

What other drugs affect Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by diphenhydramine. Tell your doctor if you regularly use any of these medicines, or any other cold or allergy medicines.

Tell your doctor about all other medications you use, especially:

  • medicines to treat high blood pressure
  • a diuretic (water pill)
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others)
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or
  • antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others

This list is not complete and there may be other drugs that can interact with diphenhydramine and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Benadryl Allergy Decongestant Dosage

How should I take Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Take this medicine with a full glass of water.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

The orally disintegrating tablets (such as Benadryl Childrens Allergy & Cold) should be placed in the mouth and allowed to dissolve. Do not swallow the disintegrating tablet whole. Allow it to dissolve in your mouth without chewing.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I overdose on Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy Decongestant (Diphenhydr Amine Pseudoephedrine)?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)

What is Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Acetaminophen is a pain reliever and fever reducer.

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, diphenhydramine, and pseudoephedrine is used to treat runny or stuffy nose, sinus congestion, sneezing, and pain or fever caused by allergies or the common cold.

Acetaminophen, diphenhydramine, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver.

Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, or pseudoephedrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

What should I discuss with my healthcare provider before taking Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Do not take this medication if you are allergic to acetaminophen, diphenhydramine, or pseudoephedrine, or to other antihistamines or decongestants, diet pills, stimulants, or ADHD medications.

Ask a doctor or pharmacist about using acetaminophen, diphenhydramine, and pseudoephedrine if you have:

  • heart disease or high blood pressure
  • liver disease, alcoholism, or cirrhosis of the liver
  • glaucoma
  • kidney disease
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy Cold Side Effects

What are the possible side effects of Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • urinating less than usual or not at all
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

  • blurred vision
  • dry mouth
  • mild loss of appetite
  • nausea, stomach pain, constipation
  • dizziness, drowsiness
  • problems with memory or concentration
  • ringing in your ears
  • restless or excitability (especially in children)
  • sleep problems (insomnia)
  • skin rash, redness, or itching; or
  • warmth, tingling, or redness under your skin

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy Cold Interactions

What other drugs affect Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Also tell your doctor if you are using any of the following drugs:

  • an antidepressant
  • a bronchodilator
  • a diuretic (water pill)
  • gout medications
  • blood pressure medication
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • seizure medication
  • isoniazid
  • zidovudine (Retrovir, AZT)
  • aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others); or
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

This list is not complete and there may be other drugs that can interact with acetaminophen, diphenhydramine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, and pseudoephedrine are contained in many combination medicines. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP, diphenhydramine, or pseudoephedrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Benadryl Allergy Cold Dosage

How should I take Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

An overdose of acetaminophen can cause serious harm. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One acetaminophen, diphenhydramine, and pseudoephedrine pill may contain up to 500 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Take this medication with food or milk if it upsets your stomach.

Drink extra fluids while you are taking acetaminophen, diphenhydramine, and pseudoephedrine.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I overdose on Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include feeling restless or nervous, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy Cold (Apap/Diphenhydramine/Pseudoephedrine)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)

What is Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Acetaminophen is a pain reliever and fever reducer.

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, diphenhydramine, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, sneezing, itchy nose, itchy or watery eyes, sore throat, cough, headache, and pain or fever caused by allergies or the common cold.

This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, diphenhydramine, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver.

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, or phenylephrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

What should I discuss with my healthcare provider before taking Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Do not take this medication if you are allergic to acetaminophen, diphenhydramine, or phenylephrine.

Ask a doctor or pharmacist if it is safe for you to use this medication if you have:

  • a cough that produces mucus (phlegm)
  • heart disease or high blood pressure
  • liver disease, alcoholism, or cirrhosis of the liver
  • glaucoma
  • kidney disease
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy & Sinus Headache Side Effects

What are the possible side effects of Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • urinating less than usual or not at all; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

  • dizziness, drowsiness
  • blurred vision
  • dry mouth
  • mild stomach pain, constipation
  • problems with memory or concentration
  • feeling restless or excited (especially in children)
  • sleep problems (insomnia); or
  • warmth, tingling, or redness under your skin

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy & Sinus Headache Interactions

What other drugs affect Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • an antidepressant
  • a bronchodilator
  • a diuretic (water pill)
  • gout medications
  • blood pressure medication
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • seizure medication
  • isoniazid
  • zidovudine (Retrovir, AZT)
  • aspirin or salicylates such as Backache Relief Extra Strength, Novasal, Nuprin Backache Caplet, Doan’s Pills Extra Strength, Tricosal, and others; or
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

This list is not complete and there may be other drugs that can interact with acetaminophen, diphenhydramine, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Avoid using an anti-itch skin cream, gel, or spray that contains diphenhydramine while you are taking this medication. Diphenhydramine can be absorbed through your skin and you may get too much if you are also taking diphenhydramine orally (by mouth).

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, and phenylephrine are contained in many combination medicines. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP, diphenhydramine, or phenylephrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Benadryl Allergy & Sinus Headache Dosage

How should I take Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

An overdose of acetaminophen can cause serious harm to your liver. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One packet of acetaminophen, diphenhydramine, and phenylephrine powder may contain up to 1000 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Take this medication with food or milk if it upsets your stomach.

Drink extra fluids while you are taking acetaminophen, diphenhydramine, and phenylephrine.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if you have severe sore throat pain that lasts longer than 2 days, or if you also have a fever, headache, nausea, vomiting, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I overdose on Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include feeling restless or nervous, dizziness, drowsiness, dry mouth, warmth or tingly feeling, and seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy & Sinus Headache (Apap/Diphenhydramine/Phenylephrine)?

Since cold or allergy medicine is usually taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com

Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)

What is Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Acetaminophen is a pain reliever and fever reducer.

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of acetaminophen, diphenhydramine, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, sneezing, itchy nose, itchy or watery eyes, sore throat, cough, headache, and pain or fever caused by allergies or the common cold.

This medication will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, diphenhydramine, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver.

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, or phenylephrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

What should I discuss with my healthcare provider before taking Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a decongestant before the MAO inhibitor has cleared from your body.

Do not take this medication if you are allergic to acetaminophen, diphenhydramine, or phenylephrine.

Ask a doctor or pharmacist if it is safe for you to use this medication if you have:

  • a cough that produces mucus (phlegm)
  • heart disease or high blood pressure
  • liver disease, alcoholism, or cirrhosis of the liver
  • glaucoma
  • kidney disease
  • diabetes
  • a thyroid disorder
  • an enlarged prostate; or
  • problems with urination

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

Benadryl Allergy & Cold Side Effects

What are the possible side effects of Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat
  • confusion, hallucinations, unusual thoughts or behavior
  • severe dizziness, anxiety, restless feeling, or nervousness
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • urinating less than usual or not at all; or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

Less serious side effects may include:

  • dizziness, drowsiness
  • blurred vision
  • dry mouth
  • mild stomach pain, constipation
  • problems with memory or concentration
  • feeling restless or excited (especially in children)
  • sleep problems (insomnia); or
  • warmth, tingling, or redness under your skin

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Benadryl Allergy & Cold Interactions

What other drugs affect Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • an antidepressant
  • a bronchodilator
  • a diuretic (water pill)
  • gout medications
  • blood pressure medication
  • medication to treat irritable bowel syndrome
  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol)
  • seizure medication
  • isoniazid
  • zidovudine (Retrovir, AZT)
  • aspirin or salicylates such as Backache Relief Extra Strength, Novasal, Nuprin Backache Caplet, Doan’s Pills Extra Strength, Tricosal, and others; or
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

This list is not complete and there may be other drugs that can interact with acetaminophen, diphenhydramine, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What should I avoid while taking Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Avoid using an anti-itch skin cream, gel, or spray that contains diphenhydramine while you are taking this medication. Diphenhydramine can be absorbed through your skin and you may get too much if you are also taking diphenhydramine orally (by mouth).

Do not use any other cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”), diphenhydramine, and phenylephrine are contained in many combination medicines. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP, diphenhydramine, or phenylephrine.

Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor’s advice, and never take more than 2 grams (2000 mg) per day.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Benadryl Allergy & Cold Dosage

How should I take Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine should be taken only for a short time until your symptoms clear up.

An overdose of acetaminophen can cause serious harm to your liver. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One packet of acetaminophen, diphenhydramine, and phenylephrine powder may contain up to 1000 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Take this medication with food or milk if it upsets your stomach.

Drink extra fluids while you are taking acetaminophen, diphenhydramine, and phenylephrine.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if you have severe sore throat pain that lasts longer than 2 days, or if you also have a fever, headache, nausea, vomiting, or skin rash.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medication at room temperature, away from heat, light, and moisture.

What happens if I overdose on Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Seek emergency medical attention if you think you have used too much of this medicine.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include feeling restless or nervous, dizziness, drowsiness, dry mouth, warmth or tingly feeling, and seizure (convulsions).

What happens if I miss a dose of Benadryl Allergy & Cold (Apap/Diphenhydramine/Phenylephrine)?

Since cold or allergy medicine is usually taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Edited from everydayhealth.com